Basic information about concerted European research on goat transmissible spongiform encaphlopathies (TSEs) or prion diseases is presented. You will find short introductions containing links to specific documents as pdf files. With these documents we want to inform public, stakeholders, policy makers like members of EFSA and SANCO, and colleagues in the scientific community. The progress reported here about goat TSE research is a concerted European product of activities performed in the Veterinary Institutes and Faculties of eight partner countries being: Cyprus, Germany, Greece, Italy, France, The Netherlands, Spain and United Kingdom.
A review paper that appeared in 2009 in the journal Veterinary Research describes the state of knowledge on goat TSEs (transmissible spongiform encephalopathies) such as scrapie, atypical scrapie and also the two cases of bovine spongiform encephalopthy (BSE). Not only the European situation but also the findings in further parts of the world have been dealt with. The paper is especially focused on the PRNP genetics and the TSE epidemiology. Part of this paper was possible through the five year Network of Excellence NeuroPrion lead by Jean Philippe Deslys in Paris, 2003-2008. It was running within the 6th framework program on Food Quality and Safety, project number FOOD-CT-2004-506579.
A subsequent project with the acronym "GoatBSE" could be acquired by the group within the same thematic priority on food safety, project number FOOD-CT-2006-36353 which ran from Dec2006-Nov2012 (cordis.europa.eu/project/rcn/85603_en.html). The GoatBSE studies were intended to assess the susceptibility for prion infectivity in goats and improve goat TSE diagnosis. An informative overall report and a summary report of year 6 are intended to inform public and policy makers.
Based on the promising results during these preceding 8-10 years, the partners were awarded additional funding within the ERA network EMIDA in the so called GOAT-TSE-FREE project (Sept. 2012-Dec. 2015) to work on some necessary missing scientific data, to involve the goat production sectors in the participating countries, to search for live genetical TSE resistance carriers, to promote breeding programs with these carriers, and to convince policy makers that outlines for such breeding could be implemented in the TSE regulations, as are already in place for sheep. The project has been finished and a summary has been placed here.
Yet, the website until now (28Aug2016) is being updated now and then. For example, the scientific literature refernece list on TSEs in goats and closely related articles is still annually being supplemented with new literature. Just click here.
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